Apheresis

At Cromwell Hospital, we provide a range of apheresis treatments including plasma exchange and red blood cell exchange.

Plasma exchange

The function of plasma is to carry blood cells (red cells, white blood cells and platelets) and various antibodies, hormones, and proteins around your body.

Plasma exchange is normally carried out when there is a problem caused by abnormal antibodies or proteins circulating in your plasma. Antibodies, which normally help to protect you from infection, can begin to attack your own healthy cells, or an over production of proteins can cause your blood to become thicker and slow down the blood flow throughout your body.

Plasma exchange is performed using a machine called a blood cell separator, which can separate blood into its various parts. The machine separates and removes the plasma portion of your blood and gives you back replacement plasma. This will normally be a processed donor plasma product, although occasionally fresh plasma will be used. The remaining parts of your blood, including red cells and white cells are returned to you during the treatment.

In order to carry out a plasma exchange, a needle will be put into a large vein in each arm. If the veins in your arms are not suitable, you may need to have a special central line inserted into a larger vein in your neck or groin under a local or general anaesthetic.

Red cell exchange

Blood is made up of red cells, white cells, and platelets, which are carried around in fluid, called plasma. Red cells carry oxygen to different parts of the body and remove waste including carbon dioxide. The red cells can be separated from the rest of your blood, removed, and replaced with red cells from blood donated by blood donors. We call this process a red cell exchange.

Red cell exchange is usually carried out when there is a problem with your own red cells called sickle cell disease. The red blood cells in people with sickle cell disease can change their shape from round to crescent (sickle) shape and as a result these abnormal red cells can block small blood vessels. This can lead to painful episodes, thrombosis (clots) and anaemia (a shortage of normal red blood cells). Red cell exchange can also be used for treating other conditions that can affect the red blood cells such as malaria and polycythaemia (too many red cells).

Red cell exchange is performed using a machine called a blood cell separator, which can separate blood into its various parts. The machine separates and removes the red cell portion of your blood and gives you back replacement red cells. The remaining part of your blood, including white cells and plasma, will be returned to you unaltered during the treatment.

In order to carry out a plasma exchange, a needle will be put into a large vein in each arm. If the veins in your arms are not suitable, you may need to have a special central line inserted into a larger vein in your neck or groin under a local or general anaesthetic.

Paying for your treatment

We welcome both self-paying and insured patients.

Our locations

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Please note - regrettably we are unable to answer specific medical questions or offer medical advice via email or telephone.